Compassionate use of voriconazole in newborn infants diagnosed with severe invasive fungal sepsis

Celik I. H., Demirel G., Oguz S. S., Uras N., Erdeve Ö., Dilmen U.

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, cilt.17, sa.6, ss.729-734, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 6
  • Basım Tarihi: 2013
  • Dergi Adı: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.729-734
  • Anahtar Kelimeler: Newborn, Invasive fungal sepsis, Voriconazole, BIRTH-WEIGHT INFANTS, NEONATAL CANDIDIASIS, ANTIFUNGAL AGENTS, INFECTION
  • Ankara Üniversitesi Adresli: Evet

Özet

BACKGROUND: Invasive fungal sepsis has become the third most common cause of late-onset infections in many neonatal intensive care units (NICU). The prevalence rate ranges from 2.6% to 16.7% among very-low-birth-weight infants and from 5.5% to 20% among extremely low-birth-weight infants. Despite the development of several new antifungal agents in the past few years, the management of serious fungal infections in the newborn continues to be problematic.