Urinary sodium excretion, blood pressure, cardiovascular disease, and mortality: a community-level prospective epidemiological cohort study

Mente, Andrew; O'Donnell, Martin; Rangarajan, Sumathy; McQueen, Matthew; Dagenais, Gilles; Wielgosz, Andreas; Lear, Scott; Ah, Shelly; Wei, Li; Diaz, Rafael; Avezum, Alvaro; Lopez-Jaramillo, Patricio; Lanas, Fernando; Mony, Prem; Szuba, Andrzej; Iqbal, Romaina; Yusuf, Rita; Mohammadifard, Noushin; Khatib, Rasha; Yusoff, Khalid; Ismail, Noorhassim; GÜLEÇ, HASAN; Rosengren, Annika; Yusufali, Afzalhussein; Kruger, Lanthe; Tsolekile, Lungiswa; Chifamba, Jephat; Dans, Antonio; Alhabib, Khalid; Yeates, Karen; Teo, Koon; Yusuf, Salim

doi:10.1016/s0140-6736(18)31376-x

Urinary sodium excretion, blood pressure, cardiovascular disease, and mortality: a community-level prospective epidemiological cohort study

Mente A., O'Donnell M., Rangarajan S., McQueen M., Dagenais G., Wielgosz A., ...Daha Fazla

LANCET, cilt.392, sa.10146, ss.496-506, 2018 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 392 Sayı: 10146
Basım Tarihi: 2018
Doi Numarası: 10.1016/s0140-6736(18)31376-x
Dergi Adı: LANCET
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.496-506
Ankara Üniversitesi Adresli: Evet

Özet

Background WHO recommends that populations consume less than 2 g/day sodium as a preventive measure against cardiovascular disease, but this target has not been achieved in any country. This recommendation is primarily based on individual-level data from short-term trials of blood pressure (BP) without data relating low sodium intake to reduced cardiovascular events from randomised trials or observational studies. We investigated the associations between community-level mean sodium and potassium intake, cardiovascular disease, and mortality.