Is Propolis a Potential Anti-Obesogenic Agent for Obesity?

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Tek N. A., Şentüre Ş. A., ERSOY N.

Current Nutrition Reports, 2024 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1007/s13668-024-00524-0
  • Dergi Adı: Current Nutrition Reports
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, Food Science & Technology Abstracts, MEDLINE
  • Anahtar Kelimeler: Creatinine kinase, Propolis, Thermogenesis, UCP-1
  • Ankara Üniversitesi Adresli: Evet

Özet

Purpose of Review: Propolis is a bee product that has been used for thousands of years. The chemical composition and biological activity of propolis, which has been investigated in the twentieth century, may vary according to location. Propolis polyphenols can induce thermogenesis in brown and beige fat tissue via the uncoupled protein-1 and creatinine kinase metabolic pathways. This review provides a comprehensive investigation of the structural and biological properties of propolis and provides insights into their promising potential strategies in body weight management. Recent Findings: By raising overall energy expenditure, it might lead to body weight management. Furthermore, the phenolic components artepillin C, quercetin, catechin, and chlorogenic acid found in its composition may have anti-obesogenic effect by stimulating the sympathetic nervous system, enhancing browning in white adipose tissue, and triggering AMP-activated protein kinase activation and mitochondrial biogenesis. Summary: Propolis, a natural product, is effective in preventing obesity which is a contemporary pandemic.