Effect of intermittent hypoxia on the cardiac HIF-1/VEGF pathway in experimental type 1 diabetes mellitus
ANATOLIAN JOURNAL OF CARDIOLOGY, cilt.16, sa.2, ss.76-83, 2016 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 16 Sayı: 2
- Basım Tarihi: 2016
- Doi Numarası: 10.5152/akd.2015.5925
- Dergi Adı: ANATOLIAN JOURNAL OF CARDIOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.76-83
- Anahtar Kelimeler: angiogenesis, diabetic cardiomyopathy, intermittent hypoxia, HIF-1, VEGF, ENDOTHELIAL GROWTH-FACTOR, INDUCIBLE FACTOR-1-ALPHA, MYOCARDIAL-ISCHEMIA, FACTOR EXPRESSION, CARDIOMYOPATHY, HEART, ANGIOGENESIS, RAT, ECHOCARDIOGRAPHY, OVEREXPRESSION
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Ankara Üniversitesi Adresli: Evet
Özet
Objective: High altitude and hypoxic preconditioning have cardioprotective effects by increasing coronary vascularity, reducing post-ischemic injury, and improving cardiac function. Our purpose was to examine if intermittent hypoxia treatment has any restoring effects related to the possible role of the HIF-1/VEGF pathway on diabetic cardiomyopathy.