A Ritter-Type Route to Diarylmethane Amides from <i>para</i>-Quinone Methides

AKYILDIZ V., SARAÇOĞLU N.

ASIAN JOURNAL OF ORGANIC CHEMISTRY, vol.12, no.6, 2023 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 6
  • Publication Date: 2023
  • Doi Number: 10.1002/ajoc.202300121
  • Journal Name: ASIAN JOURNAL OF ORGANIC CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Applied Science & Technology Source, Chemical Abstracts Core, Index Chemicus (IC), Current Chemical Reactions (CCR)
  • Ankara University Affiliated: No

Abstract

1,6-Conjugate addition/Ritter-type amidation of para-quinone methides (p-QMs) with nitriles is described. This transformation is an environmentally friendly approach by the use of NaHSO4 as a low-loading, inexpensive, green, and recyclable catalyst. Diarylmethane amides are afforded in excellent yields through a one-pot process from p-QMs and nitrile derivatives under mild reaction conditions.