Efficacy and Safety of Endoanal Ultrasound-Guided Botulinum Toxin in Chronic Anal Fissure


Akalin C., Yavuzarslan A. B., AKYOL C.

AMERICAN SURGEON, cilt.89, sa.5, ss.2125-2128, 2023 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 89 Sayı: 5
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1177/00031348211034750
  • Dergi Adı: AMERICAN SURGEON
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.2125-2128
  • Anahtar Kelimeler: chronic anal fissure, botulinum toxin, efficacy, ultrasound-guided, endoanal ultrasound, MANAGEMENT, SITE
  • Ankara Üniversitesi Adresli: Evet

Özet

We aimed to evaluate the efficacy and safety of endoanal ultrasound (EAUS)-guided botulinum toxin (BT) in the treatment of chronic anal fissure (CAF). All patients were classified into 2 groups: conventional and EAUS groups. In total, 90 units of BT were injected into the internal anal sphincter at the 3, 6, and 9 o'clock positions in the EAUS group. An injection was performed into the intersphincteric space at the 3, 6, and 9 o'clock positions in the conventional group. Adverse effects and efficacy were analyzed. There were 44 patients: 26 in the conventional group and 18 in the EAUS group. Pain and incontinence rates were similar between groups (P > .05). The efficacy rate was higher in the EAUS group (69.23%) than in the conventional group (81.82%), but this difference was not significant (P = .466). EAUS-guided BT injection is safe and effective in patients with CAFs.