Circulating IL-2, IL-10 and TNF-alpha in chronic hepatitis B: Their relations to HBeAg status and the activity of liver disease

Bozkaya H., Bozdayi M., Turkyilmaz R., Sarioglu M., Cetinkaya H., Cinar K., ...Daha Fazla

HEPATO-GASTROENTEROLOGY, cilt.47, sa.36, ss.1675-1679, 2000 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 36
  • Basım Tarihi: 2000
  • Dergi Adı: HEPATO-GASTROENTEROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1675-1679
  • Anahtar Kelimeler: hepatitis B, Th1 cytokines, Th2 cytokines, IL-2, IL-10, TNF-alpha, NECROSIS-FACTOR-ALPHA, VIRUS GENE-EXPRESSION, SERUM LEVELS, T-CELLS, INTERLEUKIN-2 ACTIVITY, ACUTE EXACERBATION, INFECTION, CYTOKINES, LYMPHOCYTES, PHENOTYPE
  • Ankara Üniversitesi Adresli: Evet

Özet

Background/Aims: Preferential production of immunoregulatory cytokines may play an important role in the pathogenesis of chronic hepatitis B. We aimed to determine the serum levels of IL-2, IL-10 and TNF-alpha in patients with chronic hepatitis B and to correlate these findings with the activity of liver disease, HBeAg/anti-HBe status and replication level of the virus.