MYCOPLASMA PNEUMONIA ENFEKSİYONU SONRASINDA GELİŞEN TOKSİK EPİDERMAL NEKROLİZİS VAKASI

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Cevizci B., Kahveci F., Havan M., Evgin M., Balaban B., Özdemir H., ...More

18.Ulusal Çocuk Acil Tıp ve Yoğun Bakım Kongresi, Antalya, Turkey, 2 - 05 November 2022, pp.1-5, (Full Text)

  • Publication Type: Conference Paper / Full Text
  • City: Antalya
  • Country: Turkey
  • Page Numbers: pp.1-5
  • Open Archive Collection: AVESIS Open Access Collection
  • Ankara University Affiliated: Yes

Abstract

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are defined as life-threatening late-onset allergic reactions. Although it is rare in children, the mortality rate is high. Factors such as infections, anticonvulsant drugs, sulfanamides and NSAIDs are thought to trigger SJS/TEN. Although there is no proven treatment protocol, removal of the suspected agent in etiology and systemic steroids, intravenous immunoglobulin (IVIG), immunosuppressive therapies such as cyclosporine and TNF-a are used in addition to supportive treatment. In this article, a case of TEN developing after M.penumonia infection that was successfully treated with IVIG, systemic steroids and immunosuppressive therapy is presented. 

Stevens-Johnson sendromu (SJS) ve toksik epidermal nekrolizis (TEN) hayatı tehdit eden geç başlangıçlı alerjik reaksiyon olarak tanımlanır. Enfeksiyonlar, antikonvülzan ilaçlar, sulfanamidler ve NSAID gibi durumların SJS/TEN tablosunu tetiklediği düşünülmektedir. Tedavisinde destek tedavisine ek olarak sistemik immünsupresif, immünomodulatör tedaviler kullanılmaktadır. Burada M.penumonia enfeksiyonu ilişkili bir TEN olgusu sunulmuştur.