Expressions of proliferation markers (Ki-67, proliferating cell nuclear antigen, and silver-staining nucleolar organizer regions) and of p53 tumor protein in gestational trophoblastic disease
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, cilt.184, sa.4, ss.567-574, 2001 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 184 Sayı: 4
- Basım Tarihi: 2001
- Doi Numarası: 10.1067/mob.2001.111243
- Dergi Adı: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.567-574
- Anahtar Kelimeler: gestational trophoblastic disease, hydatidiform mole, immunohistochemical analysis, Ki-67, p53, proliferating cell nuclear antigen, silver-staining nucleolar organizer regions, MONOCLONAL-ANTIBODY KI-67, HYDATIDIFORM MOLES, SUPPRESSOR GENE, PLACENTAS, MUTATION, MOLAR, PCNA
- Ankara Üniversitesi Adresli: Evet
Özet
OBJECTIVE: This study was undertaken to determine whether the expressions of 3 proliferation markers (Ki-67, proliferating cell nuclear antigen, and silver-staining nucleolar organizer regions) and of p53 tumor protein could differentiate spontaneous abortions from gestational trophoblastic diseases and also discriminate among gestational trophoblastic disease subgroups.