Expressions of proliferation markers (Ki-67, proliferating cell nuclear antigen, and silver-staining nucleolar organizer regions) and of p53 tumor protein in gestational trophoblastic disease

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Kale A., Soylemez F., ENSARİ A.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, cilt.184, sa.4, ss.567-574, 2001 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 184 Sayı: 4
• Basım Tarihi: 2001
• Doi Numarası: 10.1067/mob.2001.111243
• Dergi Adı: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.567-574
• Anahtar Kelimeler: gestational trophoblastic disease, hydatidiform mole, immunohistochemical analysis, Ki-67, p53, proliferating cell nuclear antigen, silver-staining nucleolar organizer regions, MONOCLONAL-ANTIBODY KI-67, HYDATIDIFORM MOLES, SUPPRESSOR GENE, PLACENTAS, MUTATION, MOLAR, PCNA
• Ankara Üniversitesi Adresli: Evet

Özet

OBJECTIVE: This study was undertaken to determine whether the expressions of 3 proliferation markers (Ki-67, proliferating cell nuclear antigen, and silver-staining nucleolar organizer regions) and of p53 tumor protein could differentiate spontaneous abortions from gestational trophoblastic diseases and also discriminate among gestational trophoblastic disease subgroups.