Expressions of proliferation markers (Ki-67, proliferating cell nuclear antigen, and silver-staining nucleolar organizer regions) and of p53 tumor protein in gestational trophoblastic disease
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, vol.184, no.4, pp.567-574, 2001 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 184 Issue: 4
- Publication Date: 2001
- Doi Number: 10.1067/mob.2001.111243
- Journal Name: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.567-574
- Keywords: gestational trophoblastic disease, hydatidiform mole, immunohistochemical analysis, Ki-67, p53, proliferating cell nuclear antigen, silver-staining nucleolar organizer regions, MONOCLONAL-ANTIBODY KI-67, HYDATIDIFORM MOLES, SUPPRESSOR GENE, PLACENTAS, MUTATION, MOLAR, PCNA
- Ankara University Affiliated: Yes
Abstract
OBJECTIVE: This study was undertaken to determine whether the expressions of 3 proliferation markers (Ki-67, proliferating cell nuclear antigen, and silver-staining nucleolar organizer regions) and of p53 tumor protein could differentiate spontaneous abortions from gestational trophoblastic diseases and also discriminate among gestational trophoblastic disease subgroups.