Early-onset severe obesity due to complete deletion of the leptin gene in a boy

ÖZSU CAVGA E., Ceylaner S., Onay H.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, cilt.30, sa.11, ss.1227-1230, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 11
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1515/jpem-2017-0063
  • Dergi Adı: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1227-1230
  • Anahtar Kelimeler: childhood, leptin, monogenic obesity, RECEPTOR, DEFICIENCY, DYSFUNCTION, CHILDREN, RESISTANCE, MUTATION
  • Ankara Üniversitesi Adresli: Hayır

Özet

Background: Monogenic obesity results from single gene mutations. Extreme obesity starting at an early age, especially in infancy, which is associated with endocrinopathy and metabolic disturbances is key to the diagnosis of monogenic obesity.