Akademik Veri Yönetim Sistemi
Turkish Journal of Gastroenterology, cilt.8, sa.2, ss.217-221, 1997 (SCI-Expanded)
In this study, efficiency and safety profile of oral sodium phosphate (NaP) were tested in patients requiring elective colonoscopy. Twenty patients were included in the study. Forty-five mL of Fleet Phospho-Soda diluted 1:1 with water was given twice at 4.00 p.m the day before the colonoscopy and 6.00 a.m. the morning of colonoscopy. To monitorize the electrolyte changes blood samples were collected during and after preparation. Patients' acceptance and efficiency of NaP were assessed. All the patients finished their preparations. 80% of patients found the preparation as easy or tolerable. Half of the patients were symptom-free and only one patient had severe nausea and vomiting. Colonoscopist completed the procedure in all cases. 95% of colons were ranked as excellent or good by means of cleaning. No change was recorded in mean serum chloride and sodium levels during and after preparation. Slight but significant hyperphosphatemia and hypocalcemia were detected after NaP administration. More severe drop was seen in serum potassium level. Changes in electrolytes tended to normalize in the latest serum samples. In conclusion, NaP has a high patients' acceptance and is an effective agent for colon cleansing. Its hypopotassemic effect may be more important than the other electrolyte abnormalities at the clinical settings.