Akademik Veri Yönetim Sistemi
Asian Journal of Chemistry, cilt.30, sa.11, ss.2567-2570, 2018 (SCI-Expanded)
© 2018 Chemical Publishing Co. All rights reserved.The UV absorption spectra were processed by using the continuous wavelet transform for the determination of dexamethasone in tablets. In order to get optimal wavelet transform, some wavelet families were tested to transform the UV-absorption spectra of the related drug in the spectral region of 210.0-312.3 nm. In the test procedure of wavelet families, it was observed that Mexican hat function-continuous wavelet transform (mexh-CWT) and Daubechies 8-continuous wavelet transform (db8-CWT) were appropriate for the UV spectra for the quantitative estimation of dexamethasone. The validity of proposed continuous wavelet transform signal analysis methods were performed by using the analysis results of the solutions for validation samples. In the method validation studies, the percent recoveries and their relative standard deviations were found as 100.7 % and 0.78 for mexh-CWT procedure and 100.2 % and 1.28 for db8-CWT procedure. It was concluded that both mexh-CWT and db8-CWT methods were useful approaches for the determination of dexamethasone in tablets.