Successful Desensitization of a Patient with Rituximab Hypersensitivity
CASE REPORTS IN IMMUNOLOGY, cilt.2015, 2015 (ESCI)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 2015
- Basım Tarihi: 2015
- Doi Numarası: 10.1155/2015/524507
- Dergi Adı: CASE REPORTS IN IMMUNOLOGY
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Ankara Üniversitesi Adresli: Evet
Özet
Rituximab is a monoclonal antibody which targets CD20 in B cells that is used for the treatment of CD20 positive oncologic and hematologic malignancies. Rituximab causes hypersensitivity reactions during infusions. The delay of treatment or loss of a highly efficient drug can be prevented by rapid drug desensitization method in patients who are allergic to rituximab. We report a low grade B cell non-Hodgkin lymphoma patient with rituximab hypersensitivity successfully treated with rapid drug desensitization. In experienced centers, drug desensitization is a novel modality to break through in case of hypersensitivity that should be considered.