Clinical Significance of Serum Vascular Endothelial Growth Factor, Pigment Epithelium-Derived Factor, Tumor Necrosis Factor Alpha, and Progranulin Levels in Patients with Gastric Cancer and Gastric Precancerous Lesions

Aksoy, Evrim; Akpinar, Muhammet; DOĞAN, ÖZLEM; GÖKTAŞ, ZEYNEP; Sapmaz, Ferdane; Simsek, Gulcin; Uzman, Metin; Nazligul, Yasar

doi:10.1007/s12029-019-00251-8

Clinical Significance of Serum Vascular Endothelial Growth Factor, Pigment Epithelium-Derived Factor, Tumor Necrosis Factor Alpha, and Progranulin Levels in Patients with Gastric Cancer and Gastric Precancerous Lesions

Aksoy E. K., Akpinar M. Y., DOĞAN Ö., GÖKTAŞ Z., Sapmaz F. P., Simsek G. G., ...Daha Fazla

JOURNAL OF GASTROINTESTINAL CANCER, cilt.50, sa.3, ss.537-542, 2019 (ESCI, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 50 Sayı: 3
Basım Tarihi: 2019
Doi Numarası: 10.1007/s12029-019-00251-8
Dergi Adı: JOURNAL OF GASTROINTESTINAL CANCER
Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
Sayfa Sayıları: ss.537-542
Anahtar Kelimeler: Gastric cancer, Gastric atrophy, Intestinal metaplasia, VEGF, PEDF, TNF-alpha, Progranulin, EXPRESSION, IDENTIFICATION, ANGIOGENESIS
Ankara Üniversitesi Adresli: Evet

Özet

Background The purpose of this study is to evaluate serum levels of vascular endothelial growth factor (VEGF), pigment epithelium-derived factor (PEDF), tumor necrosis factor alpha (TNF-alpha), and progranulin in patients with gastric cancer (GC) and precancerous lesions (PCL) and to determine the usefulness of these markers as diagnostic biomarkers in these diseases.