Relationship of paraoxonase-1, malondialdehyde and mean platelet volume with markers of atherosclerosis in familial Mediterranean fever: an observational study

Ariturk O. K., ÜRETEN K., Sari M., YAZIHAN N., Ermis E., Erguder I.

ANATOLIAN JOURNAL OF CARDIOLOGY, cilt.13, sa.4, ss.357-362, 2013 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 13 Sayı: 4
  • Basım Tarihi: 2013
  • Doi Numarası: 10.5152/akd.2013.103
  • Dergi Adı: ANATOLIAN JOURNAL OF CARDIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.357-362
  • Anahtar Kelimeler: Familial Mediterranean fever, atherosclerosis, paraoxonase, mean platelet volume, malondialdehyde, INTIMA-MEDIA THICKNESS, SERUM PARAOXONASE, ARYLESTERASE ACTIVITIES, OXIDATIVE STRESS, INFLAMMATION, ASSOCIATION, PREVALENCE, ARTHRITIS, SEVERITY, DISEASE
  • Ankara Üniversitesi Adresli: Evet

Özet

Objective: There are many studies demonstrating deteriorated ventricle and endothelium functions in familial Mediterranean fever (FMF) patients. As FMF is an autoinflammatory disease with an ongoing inflammatory activity and inflammation plays an important role in the development and progression of atherosclerosis in some of the rheumatic diseases, we aimed to investigate the early markers of atherosclerosis in patients with FMF by the measurements of serum paraoxonase-1 (PON-1) activity mean platelet volume (MPV) and malondialdehyde (MDA) level.