The longest infectious virus shedding in a child infected with the G614 strain of SARS-COV-2

Bal Z. S., ÖZKUL A., Bilen M., Kurugol Z., Ozkinay F.

Pediatric Infectious Disease Journal, vol.40, no.7, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 40 Issue: 7
  • Publication Date: 2021
  • Doi Number: 10.1097/inf.0000000000003158
  • Journal Name: Pediatric Infectious Disease Journal
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Keywords: SARS-CoV-2, COVID-19, infectious virus, shedding, child
  • Ankara University Affiliated: Yes

Abstract

Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.COVID-19 spread globally and caused over 97 million cases with more than 2 million deaths. There is still ongoing discussion on the duration of infectious interval SARS-CoV-2 infection. Symptomatic children had longer virus shedding and there are some reports of prolonged infectious virus shedding in adults particularly patients having an immunocompromised status. A missense mutation, D614G, in the spike protein of SARSCoV-2, which has emerged as a predominant clade in Europe and is spreading worldwide that can result in higher viral loads in patients. Herein, we described the longest infectious virus shedding in a previously healthy child infected with SARS-CoV-2 expressing spike D614G substitution.