Determination of Vulpinic Acid Effect on Apoptosis and mRNA Expression Levels in Breast Cancer Cell Lines

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Kilic N., Aras S., CANSARAN DUMAN D.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, vol.18, no.14, pp.2032-2041, 2018 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 18 Issue: 14
• Publication Date: 2018
• Doi Number: 10.2174/1871520618666180903101803
• Journal Name: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.2032-2041
• Keywords: Vulpinic acid, breast cancer, apoptosis, qRT-PCR, Lichen secondary metabolites, SK-BR-3 cell lines, USNIC ACID, LICHEN, METABOLITES, MEMBRANE, PROFILES, GROWTH
• Ankara University Affiliated: Yes

Abstract

Objective: Breast cancer is one of the most common diseases among women worldwide and it is characterized by a high ratio of malignancy and metastasis and low rate of survival of patients. Due to limited treatment options, the discovery of alternative therapeutic agents and clarifying the molecular mechanism of breast cancer development may offer new hope for its treatment. Lichen secondary metabolites may be one of these therapeutic agents.