Bisphosphonate induced osteonecrosis of the maxilla: A case report Bifosfonat kullanimina bagli olarak maksillada kemik nekrozu olusumu: Bir olgu sunumu

Öncül A. M. T., Şahin S., Görür D. I., ÖZTÜRK A., ORHAN K.

Cumhuriyet Dental Journal, vol.13, no.1, pp.4-8, 2010 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 1
  • Publication Date: 2010
  • Journal Name: Cumhuriyet Dental Journal
  • Journal Indexes: Scopus, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.4-8
  • Keywords: Bisphosphonates, Osteonecrosis
  • Ankara University Affiliated: Yes


Purpose: Bisphophonates are used in the management of metastatic bone cancers and osteoporosis. Intravenous (i.v) bisphosphonate (pamidronate, zoledronate) treatment causes the osteonecrosis of the jaws. In this case report, treatment of a referred patient, is presented. Case Report: A 51 years old female patient referred to our department with asymptomatic ostonecrosis in her left maxilla as a consequence of long term i.v. Bisphosphonates consumption. The treatment protocol included debridement, sequestrectomy and hyperbaric oxygen therapy. The patient has followed up periodically. Conclusion: Occurrence of bisphosphonate induced osteonecrosis became frequent by the increase of i.v. Biphosphonate usage. Therefore, the patients who will be treated by bisphosphonates must consult to a dentist and all dental treatments must be completed before the beginning of the therapy. By this way, the complications can be prevented.