Voltammetric determination of droperidol and benperidol

Biryol I., Ozkan S. A.

Journal of Pharmaceutical and Biomedical Analysis, vol.15, no.11, pp.1695-1701, 1997 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 11
  • Publication Date: 1997
  • Doi Number: 10.1016/s0731-7085(96)01966-8
  • Journal Name: Journal of Pharmaceutical and Biomedical Analysis
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1695-1701
  • Keywords: droperidol, benperidol, platinum electrode, glassy carbon electrode, determination, HUMAN-PLASMA, BUTYROPHENONES, ELECTRODE, DRUGS
  • Ankara University Affiliated: Yes

Abstract

In this study two butyrophenones, droperidol and benperidol were voltammetrically investigated using platinum and specially activated glassy carbon electrodes. The behaviours of the substances were investigated in various electrolyte solutions having different pH values and by different scan rates. As a result of the studies it was shown that the quantitative determinations of the substances from their pharmaceutical preparations could be made rapidly and simply without any separation from the excipients.