Serum leptin levels are associated with tamoxifen-induced hepatic steatosis

Gunel N., Coskun U., Toruner F., Sancak B., Yilmaz E., Cengiz O., ...More

CURRENT MEDICAL RESEARCH AND OPINION, vol.19, no.1, pp.47-50, 2003 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 1
  • Publication Date: 2003
  • Doi Number: 10.1185/030079902125001308
  • Journal Name: CURRENT MEDICAL RESEARCH AND OPINION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.47-50
  • Keywords: breast cancer, hepatic steatosis, leptins, tamoxifen, BREAST-CANCER PATIENTS, NONALCOHOLIC STEATOHEPATITIS, POSTMENOPAUSAL PATIENTS, WOMEN, HYPERTRIGLYCERIDEMIA, THERAPY, WEIGHT
  • Ankara University Affiliated: Yes

Abstract

Purpose: Tamoxifen, used in breast cancer treatment, may induce hepatic steatosis. It has been suggested that leptin, which, has a relationship with body fat stores, may be involved in the pathogenesis of hepatic steatosis. In this study, we compared serum leptin levels in tamoxifen-treated patients with and without hepatic steatosis.