Successful treatment of Trichosporon mucoides infection with lipid complex amphotericin B and 5-fluorocytosine

Kendirli T., ÇİFTCİ E., Ince E., ÖNCEL S., Dalgic N., Guriz H., ...More

MYCOSES, vol.49, no.3, pp.251-253, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 3
  • Publication Date: 2006
  • Doi Number: 10.1111/j.1439-0507.2006.01223.x
  • Journal Name: MYCOSES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.251-253
  • Keywords: Trichosporon mucoides, sepsis, lipid complex amphotericin B, 5-fluorocytosine
  • Ankara University Affiliated: Yes

Abstract

Infections in immunocompromised children can stem from bacteria, fungi, viruses, or protozoa, but most importantly, from the host's endogenous bacterial flora. Disseminated infection caused by Trichosporon species is one of the emerging mycoses in neutropenic patients, particularly when they are treated for haematological malignancy with cytotoxic and immunosuppressive chemotherapy. We report a 15-year-old boy with acute lymphoblastic leukaemia, whose Trichosporon mucoides infection was successfully treated with lipid complex amphotericin B plus 5-fluorocytosine.