Prevalence and risk factors for selection of quinolone-resistant escherichia coli strains in fecal flora of patients receiving quinolone therapy

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Yagci D., Yoruk F., Azap A., Memikoglu O.

Antimicrobial Agents and Chemotherapy, vol.53, no.3, pp.1287-1289, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 53 Issue: 3
  • Publication Date: 2009
  • Doi Number: 10.1128/aac.01228-08
  • Journal Name: Antimicrobial Agents and Chemotherapy
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1287-1289
  • Ankara University Affiliated: Yes


Patients taking quinolones as inpatients (n=55) or outpatients (n = 40) and newly hospitalized patients who were not on quinolone therapy (n = 41) were assessed for fecal carriage of quinolone-resistant Escherichia coli (QREC) strains before and after therapy/hospitalization. Fluoroquinolone use in the previous 6 months was found to be a risk factor for QREC carriage before therapy/hospitalization. The prevalence of QREC strains in fecal flora increased steadily with the duration of quinolone therapy. Copyright © 2009, American Society for Microbiology. All Rights Reserved.