Behcet's syndrome and relationship with the ratio of insulin-like growth factor-1 (IGF-1)/IGF-binding protein-3 (IGFBP-3)

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DOĞAN Ö., Unal E., KISA Ü., Aksoy N.

POSTEPY DERMATOLOGII I ALERGOLOGII, vol.36, no.3, pp.295-301, 2019 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 36 Issue: 3
  • Publication Date: 2019
  • Doi Number: 10.5114/ada.2019.85640
  • Journal Name: POSTEPY DERMATOLOGII I ALERGOLOGII
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.295-301
  • Keywords: Behcet's syndrome, insulin like growth factor-1, IGF-binding protein-3, inflammation, IGF-1/IGFBP-3 MOLAR RATIO, IGF-BINDING PROTEIN-3, SERUM-LEVELS, RESISTANCE, RESTRICTION
  • Ankara University Affiliated: Yes

Abstract

Introduction: Behcet's syndrome (BS) is a chronic inflammatory disease with unknown aetiology. Insulin-like growth factor-1 (IGF-1) and IGF-binding protein-3 (IGFBP-3) have important metabolic properties such as anabolic, cytoprotective and anti-inflammatory effects. Circulating IGF-1 and IGF-1/IGFBP-3 concentrations are associated with adiposity and insulin resistance.