Concentrated platelet-rich plasma used in root canal revascularization: 2 case reports

Bezgin T., Yilmaz A. D., Celik B. N., Sonmez H.

INTERNATIONAL ENDODONTIC JOURNAL, vol.47, no.1, pp.41-49, 2014 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 1
  • Publication Date: 2014
  • Doi Number: 10.1111/iej.12144
  • Journal Name: INTERNATIONAL ENDODONTIC JOURNAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.41-49
  • Keywords: concentrated platelet-rich plasma, immature teeth, revascularization, IMMATURE PERMANENT TEETH, ENDODONTIC TREATMENT REVASCULARIZATION, APICAL PERIODONTITIS, NECROTIC PULP, OPEN APEX, TOOTH, REVITALIZATION, MOLARS
  • Ankara University Affiliated: Yes

Abstract

AimTo present two case reports describing the treatment of immature teeth with necrotic pulps using concentrated platelet-rich plasma (cPRP) with 12-month clinical and radiographic follow-up. SummaryRoot canal revascularization was performed on immature permanent teeth clinically and radiographically diagnosed as requiring root canal treatment. Following disinfection of the canal space with triple antibiotic paste (1:1:1: ciprofloxacin, metronidazole and cefaclor), a tissue scaffold was created with cPRP prepared using 2-step centrifugation. The final restoration was completed with white mineral trioxide aggregate and composite resin. The patients were recalled for clinical and radiographic evaluations every 3months. At the 12-month follow-up apical closure by narrowing of the apical foramen and convergence of the apical walls in the treated teeth was observed. Key learning points Concentrated platelet-rich plasma (cPRP) was successful as a scaffold in revascularization treatment. 2-step centrifugation was a simple and useful technique to prepare PRP.