Recent Developments in the Sensitive Electrochemical Assay of Common Opioid Drugs


Yence M., Cetinkaya A., Kaya S. I., ÖZKAN S. A.

CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY, vol.54, no.4, pp.882-895, 2024 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 54 Issue: 4
  • Publication Date: 2024
  • Doi Number: 10.1080/10408347.2022.2099732
  • Journal Name: CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Aqualine, Aquatic Science & Fisheries Abstracts (ASFA), Biotechnology Research Abstracts, Chemical Abstracts Core, Chimica, Communication Abstracts, Compendex, EMBASE, Environment Index, Geobase, MEDLINE, Metadex, Civil Engineering Abstracts
  • Page Numbers: pp.882-895
  • Keywords: Common opioid drugs, detection methods, electrochemical detection, opioid overuse, WALLED CARBON NANOTUBES, MOLECULARLY IMPRINTED POLYMER, HUMAN URINE, PASTE ELECTRODE, IONIC LIQUID, BIOLOGICAL-FLUIDS, SELECTIVE DETERMINATION, PHARMACEUTICAL SAMPLES, UNITED-STATES, CHRONIC PAIN
  • Ankara University Affiliated: Yes

Abstract

Opioids are a class of drugs used to treat moderate to severe pain and have short-term adverse effects. Nevertheless, they are considered necessary for pain management. However, well-known hazards are connected with an opioid prescription, such as overuse, addiction, and overdose deaths. For example, the death rate from opioid analgesic poisoning in the USA approximately doubled, owing to the overuse and addiction of opioid analgesics. Also, opioids are a very important group of analytes in forensic chemistry, so it is necessary to use reliable, fast, and sensitive analytical tools to determine opioid analgesics. This review focuses on the opioid overdose crisis, the properties of commonly used opioid drugs, their mechanism, effects, and some chromatographic and spectroscopic detection methods are explained briefly. Then most essentially recent developments covering the last ten years in the sensitive electrochemical methods of common opioid analgesics, their innovations and features, and future research directions are presented.