Synthesis and antimicrobial evaluation of some 3-(substituted phenacyl)-5-[4 '-(4H-4-oxo-1-benzopyran-2-yl)-benzylidene]-2,4-thiazolidinediones


Tuncbilek M., Altanlar N.

FARMACO, vol.54, no.7, pp.475-478, 1999 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 54 Issue: 7
  • Publication Date: 1999
  • Doi Number: 10.1016/s0014-827x(99)00054-3
  • Journal Name: FARMACO
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Index Chemicus (IC)
  • Page Numbers: pp.475-478
  • Keywords: flavonylthiazolidinediones, antimicrobial activity, SUBSTITUTED THIAZOLIDINEDIONES, FLAVONOIDS
  • Ankara University Affiliated: Yes

Abstract

Synthesis and in vitro antimicrobial activity of some 3-(substituted phenacyl)-5-[4'(4H-4-oxo-1-benzopyran-2-yl)-benzylidene]-2,4-thiazolidinedione derivatives are described. These products were synthesized by the Knoevenagel reaction from 4'-flavone carboxaldehyde and 3-substituted phenacyl-2,4-thiazolidinediones. (C) 1999 Elsevier Science S.A. All rights reserved.