Effectiveness of Antibiotics Given to Asymptomatic Men for an Increased Prostate Specific Antigen

Baltaci S., SÜER E., Haliloglu A. H., GÖKCE M. İ., ELHAN A. H., Beduek Y.

JOURNAL OF UROLOGY, vol.181, no.1, pp.128-132, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 181 Issue: 1
  • Publication Date: 2009
  • Doi Number: 10.1016/j.juro.2008.09.020
  • Journal Name: JOURNAL OF UROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.128-132
  • Keywords: prostate-specific antigen, anti-bacterial agents, prostatic neoplasms, ANTIBACTERIAL THERAPY, PSA LEVELS, SERUM PSA, INFLAMMATION, CANCER, LEVEL, NG/ML
  • Ankara University Affiliated: Yes

Abstract

Purpose: Although there is controversy surrounding this subject, some urologists in daily practice often prescribe antibiotics before biopsy to men with a newly increased prostate specific antigen. We evaluated the effects of antibiotics on serum total prostate specific antigen, free prostate specific antigen, percent free prostate specific antigen and prostate specific antigen density in men with prostate specific antigen between 4 and 10 ng/ml and normal digital rectal examination. We also investigated the incidence of prostate cancer after antibiotic treatment by performing prostate biopsies in all patients regardless of posttreatment prostate specific antigen.