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Karatayli S. C., Bozdayi M., Karatayli E., ÖZTÜRK T., Husseini A. A., ALBAYRAK DELİALİOĞLU R., ...More
LIVER INTERNATIONAL, vol.35, no.3, pp.846-853, 2015 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
35
Issue:
3
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Publication Date:
2015
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Doi Number:
10.1111/liv.12595
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Journal Name:
LIVER INTERNATIONAL
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Page Numbers:
pp.846-853
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Keywords:
hepatitis B infection, hepatitis delta infection, interferon lambda 3, interleukin 28 B, single nucleotide polymorphisms, GENOME-WIDE ASSOCIATION, NATURAL-HISTORY, CHRONIC HBV, HEPATOCELLULAR-CARCINOMA, ANTIGEN SEROCLEARANCE, INTERFERON-ALPHA, HLA-DP, VIRUS, IL28B, DELTA
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Ankara University Affiliated:
Yes
Abstract
Background & AimsAim of this study was to investigate whether a potential association exists between several single nucleotide polymorphisms (SNPs) of the IL-28B gene (rs12979860, rs1188122, rs8099917, rs8105790, rs12980275) and HBsAg persistence. Further, a potential effect on the development of HBeAg-negative CHB vs. inactive HBsAg carrier state was assessed in a genotype D HBV cohort. A cohort of chronic HDV patients was also used to see if they behave differently compared to chronic HBV patients.