Akademik Veri Yönetim Sistemi
Turk Hijyen ve Deneysel Biyoloji Dergisi, cilt.74, ss.41-48, 2017 (Scopus, TRDizin)
Objective: In this study, it has been aimed to develop a fast, reliable, efficient and easy method in order to determine quantitative pesticides in tap water, drinking water, natural spring water and natural mineral waters without any extraction but with direct injection into triple liquid chromatography and quadrupole mass spectrometer (LC-MS/MS) instrumentation. Methods: 15 samples of drinking-using water (tap water), five samples of drinking water, 15 samples of spring water and 15 samples of natural mineral waters, which are all in the scope of Regulation Concerning Water Intended for Human Consumption and Regulation on Natural Mineral Waters, have been analyzed for 30 pesticides by directly injecting into LC-MS/MS instrumentation without any extraction process. Results have been assessed statistically. Results: In pesticide analysis, it is quite important to analyze as much analytes as possible in one method in order to save time and reduce cost of chemicals and consumables. In the study, linearity,quantitation and detection limits, validity, repeatability, reproducibiliy and recovery parameters of the developed method have been calculated in order to reflect its performance. Through the method developed, synchronous analysis of pesticides have been performed with a 0.020 μg/L - 0.1 μg/L detection limit. Conclusion: The Regulation Concerning Water Intended for Human Consumption is the given maximum residue limits in drinking-using water, drinking water and natural spring waters are; 0.10 μg/L for pesticides, 0.50 μg/L for total pesticides and 0.030 μg/L for aldrin, dieldrin, heptachlor and heptachlor epoxide. Maximum acceptability limit for pesticides in the Regulation on Natural Mineral Waters is defined as 0.10 μg/L. A fast, reliable, efficient and easy method has been developed in this study to determine pesticides in waters without any extraction but with direct injection into LC-MS/ MS instrumentation in ESI(+) (electrospray ionization positive) mode. Detection limit of the method to analyze for 30 pesticides is 0.020 μg/L - 0.1 μg/L. The method developed meets the limits of the current regulations in force regarding pesticide determination in drinking-using water, drinking water, natural spring water and natural mineral waters.