Skin Localization of Lipid Nanoparticles (SLN/NLC): Focusing the Influence of Formulation Parameters

AMASYA G., Sandri G., BEŞİKCİ A., BADILLI F. U., Caramella C., Bonferoni M. C., ...More

CURRENT DRUG DELIVERY, vol.13, no.7, pp.1100-1110, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 7
  • Publication Date: 2016
  • Doi Number: 10.2174/1567201813666160104130505
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1100-1110
  • Keywords: Confocal microscopy, dermal drug delivery, fluorescein, hydrophilic drug, lipid nanoparticles, NLC, SLN, DRUG-DELIVERY, CARRIERS NLC, IN-VITRO, TOPICAL DELIVERY, PENETRATION, CANCER, 5-FLUOROURACIL, COENZYME-Q10, SYSTEMS, CELLS
  • Ankara University Affiliated: Yes


Background: In this study, fluorescein labeled SLN and NLC formulations were prepared for improving the dermal distribution of the hydrophilic active ingredients and for enhancing the skin penetration.