Boron-Doped Diamond Electrodes: Recent Developments and Advances in View of Electrochemical Drug Sensors

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Yence M., Cetinkaya A., Özçelikay G., Kaya S. I., Özkan S. A.

CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY, vol.52, no.5, pp.1122-1138, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 52 Issue: 5
  • Publication Date: 2022
  • Doi Number: 10.1080/10408347.2020.1863769
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Aqualine, Aquatic Science & Fisheries Abstracts (ASFA), Biotechnology Research Abstracts, Chemical Abstracts Core, Chimica, Communication Abstracts, Compendex, EMBASE, Environment Index, Geobase, MEDLINE, Metadex, Civil Engineering Abstracts
  • Page Numbers: pp.1122-1138
  • Keywords: Boron-doped diamond, pretreatment, carbon materials, drug analysis, voltammetry
  • Ankara University Affiliated: Yes


Conductive boron-doped diamond (BDD), in addition to its superior material properties, offers many important advantages that make it an interesting material for electroanalytical studies. It has been considered as an excellent electrode material for electrooxidation of drug active compounds in their dosage forms or in biological materials due to its good physical and chemical properties. It contains not only the largest solvent working potential window compared to other electrode materials, but also it has low background and capacitive currents; lower problems with passivation and it has the ability to withstand extreme potentials, corrosive, and high temperature/pressure environments. The aim of this review is not only to provide a state-of-the-art of diamond electrochemistry but also to serve as a reference point for any researcher wishing to commence work with diamond electrodes and understand electrochemical data. Therefore, it is focused on the carbon-based materials, electrochemical properties of the BDD film electrode, its fundamental research, and its electrochemical pretreatment process are discussed in detail. In this case, there are important studies to show the effective BDD drug sensors for the detection and determination of drugs and the present review critically summarizes the available data in this field between 2015 and 2020.