Molecular characterization of bovine noroviruses and neboviruses in Turkey: detection of recombinant strains


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KARAYEL HACIOĞLU İ., ALKAN F.

ARCHIVES OF VIROLOGY, vol.164, no.5, pp.1411-1417, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 164 Issue: 5
  • Publication Date: 2019
  • Doi Number: 10.1007/s00705-019-04186-0
  • Journal Name: ARCHIVES OF VIROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1411-1417
  • Ankara University Affiliated: Yes

Abstract

To investigate the molecular epidemiology and genetic diversity of bovine enteric caliciviruses, a total of 167 fecal samples from diarrheic calves were screened. Bovine noroviruses (BoNoVs) and neboviruses were detected in 56 (33.5%) and 37 (22.1%) fecal samples, respectively. Sequences of the RdRp and capsid gene of selected BoNoVs showed that the GIII.1 and GIII. 2 genotypes were in circulation in Turkey. Two of the BoNoV strains were identified as recombinant strains (GIII. P1/GIII.2). All examined neboviruses possessed a Nebraska-like RdRp gene. The two nebovirus strains were classified into lineage 4 based on phylogenetic analysis of VP1 amino acid sequences. One of them showed evidence of a recombination event within the S domain. This study is thus the first to reveal the presence of the BoNoV GIII. 1 genotype and recombinant strains of BoNoV and neboviruses in Turkey.