Use of percent free prostate-specific antigen density to improve the specificity for detecting prostate cancer in patients with normal rectal examinations and intermediate prostate-specific antigen levels.

Baltaci S., Aksoy H., Turkolmez K., ELHAN A. H., Ozden E., Gogus O.

Urologia internationalis, vol.70, no.1, pp.36-41, 2003 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 70 Issue: 1
  • Publication Date: 2003
  • Doi Number: 10.1159/000067700
  • Journal Name: Urologia internationalis
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.36-41
  • Keywords: prostate, carcinoma, prostate-specific antigen, prostatic neoplasms, free PSA density, TOTAL PSA, SERUM, VOLUME, ASSAYS, RATIO, MULTICENTER, HYPERPLASIA, CARCINOMA, MEN, AGE
  • Ankara University Affiliated: Yes

Abstract

Introduction: As prostatic volume influences percent free prostate-specific antigen (PSA) in patients with prostate cancer, we evaluated whether percent free PSA density, which relates the serum percent free PSA to the volume of the prostate determined by transrectal ultrasound, could increase the specificity of cancer detection in men with normal digital rectal examinations and intermediate PSA levels.