Title: Oral Cancers: A Case Series of Three Patients

Çalkap B. Ş., Efeoğlu S., Aktaş A.

International Association of DentoMaxilloFacial Radiology, Venice, İtalya, 16 - 18 Ekim 2025, (Özet Bildiri)

  • Yayın Türü: Bildiri / Özet Bildiri
  • Basıldığı Şehir: Venice
  • Basıldığı Ülke: İtalya
  • Ankara Üniversitesi Adresli: Evet

Özet

Aim

This study aims to present three distinct oral cancer cases involving different anatomical regions of the oral cavity and to highlight the importance of early diagnosis and a multidisciplinary approach in optimizing treatment outcomes and patient survival.


Materials and Methods

Three patients diagnosed with oral malignancies were included: two with oral squamous cell carcinoma (OSCC) and one with osteosarcoma. The patients were aged 33, 40, and 53 years; one was female and two were male. Clinical examination, medical history, radiological imaging (CBCT and/or MRI), and histopathological evaluation were performed.


The 53-year-old male patient had a history of smoking and was previously treated for lymphoma with chemotherapy and stem cell transplantation 10 years prior. Following diagnosis, all patients were referred for further oncological evaluation and management.


Results

All three patients presented with a common finding: a painless intraoral swelling with central ulceration that had not healed over time.


Lesion locations and final diagnoses were:


Case 1 (33 y/o, female): Osteosarcoma of the buccal mucosa


Case 2 (53 y/o, male): OSCC of the maxillary molar region, with risk factors (smoking, immunosuppression)


Case 3 (40 y/o, male): OSCC of the mandibular molar region


All diagnoses were confirmed through histopathological analysis after imaging. Patients began treatment and follow-up at specialized centers.


Conclusions

Early diagnosis of oral cancers is crucial for improving survival rates and treatment success. Dentists play a key role in detecting suspicious intraoral lesions early. Persistent, non-healing, or atypical lesions should be thoroughly examined, and biopsy performed when necessary. If malignancy is suspected, immediate referral to appropriate specialists is essential. A multidisciplinary, proactive approach significantly improves patient outcomes and reduces mortality.