An unusual case of vancomycin-related systemic reaction accompanied with severe thrombocytopenia mimicking pacemaker-related infective endocarditis: a case report and review of literature

CANDEMİR B., Acibuca A., Koca C., Ozcan O. U., Gerede M., TULUNAY KAYA C.

JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY, vol.38, no.2, pp.143-145, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 38 Issue: 2
  • Publication Date: 2013
  • Doi Number: 10.1007/s10840-012-9738-6
  • Journal Name: JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.143-145
  • Keywords: Implantable cardioverter defibrillator, Infective endocarditis, Hematoma, Vancomycin, Thrombocytopenia, DRUG-INDUCED THROMBOCYTOPENIA
  • Ankara University Affiliated: Yes

Abstract

Vancomycin is a glycopeptide antibiotic used in the prophylaxis and treatment of infections caused by Gram-positive resistant bacteria. In recent years, several cases of vancomycin-associated immune thrombocytopenia have been presented as case reports, but the real incidence of this side effect is still unknown. In this report, we would like to present a case during which we confronted with a great dilemma: urgent removal of whole defibrillator system due to highly suspected infective endocarditis or leaving the defibrillator in place and simply switching vancomycin to another antibiotic agent and wait.