New brand MXene-based electrochemical point-of-care sensors as novel diagnostic devices

Karadurmus L., Kaya S. I., Cetinkaya A., ÖZKAN S. A.

TrAC - Trends in Analytical Chemistry, vol.165, 2023 (SCI-Expanded) identifier

  • Publication Type: Article / Review
  • Volume: 165
  • Publication Date: 2023
  • Doi Number: 10.1016/j.trac.2023.117145
  • Journal Name: TrAC - Trends in Analytical Chemistry
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Analytical Abstracts, Chemical Abstracts Core, Chimica, Compendex, EMBASE, Food Science & Technology Abstracts, DIALNET
  • Keywords: Diagnostic devices, Electrochemical point-of-care sensors, MXenes, Point-of-care testing
  • Ankara University Affiliated: Yes


Lack of timely detection or proper monitoring of diseases is still one of the most important causes of death. Developing a portable device that is small, easy to use, and can follow various parameters and factors similar to a portable laboratory is crucial for rapidly diagnosing diseases. Electroanalytical methods stand out among other methods with their easy application, low cost, high sensitivity, and ease of use. Nanomaterials are valuable materials for point-of-care (POC) diagnostics because of their excellent chemical, electrical, electrocatalytic, and physical features. This review overviews the most significant studies on electrochemical POC diagnostics using Mxenes in the last five years. Thanks to this comprehensive review, the researchers will gain an overview of sensitive, selective, low cost and effective analysis methods for electrochemical analysis. Detailed information will be given on how selectivity and sensitivity can be improved in Mxenes-based electrochemical POC sensor studies. Recent studies in this review will be discussed in detail in terms of novel diagnostic devices. Researchers will also find various experimental parameters and the methods used in the electrochemical analysis. In addition, this review will provide great convenience to researchers in finding up-to-date resources for electroanalytical analysis.