Congenital melanocytic naevi: An up-to-date overview

Farabi B., AKAY B. N., Goldust M., Wollina U., Atak M. F., Rao B.

AUSTRALASIAN JOURNAL OF DERMATOLOGY, vol.62, no.2, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 62 Issue: 2
  • Publication Date: 2021
  • Doi Number: 10.1111/ajd.13535
  • Journal Name: AUSTRALASIAN JOURNAL OF DERMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE
  • Keywords: classification, congenital melanocytic naevi, dermatoscopy, dermoscopy, follow-up, genetics, management, neurocutaneous melanocytosis, reflectance confocal microscopy, surgery, treatment, NEUROCUTANEOUS MELANOSIS, MALIGNANT-MELANOMA, PROLIFERATIVE NODULES, DERMOSCOPIC FEATURES, TREATMENT MODALITIES, CUTANEOUS MELANOMA, RISK, MUTATIONS, PATTERNS, CHILDREN
  • Ankara University Affiliated: Yes

Abstract

Congenital melanocytic naevi are hamartomas of the neuroectoderm caused by genetic mosaicism. Congenital melanocytic naevi are seen in 1-6% of all live births and commonly classified based on the projected size in adults. Congenital melanocytic naevi appear in different colours, shapes, and sizes, and occasionally present with complications. In this review, we sought to evaluate congenital melanocytic naevi, their clinical, dermatoscopic, and reflectance confocal microscopic features, behavioural pattern over time, new trends in classification, underlying genetic factors and their influence on clinical manifestations and management, associated risks, complications, magnetic resonance imaging findings and their management in the light of recent literature.