Synthesis and antimicrobial activity of some new anilino benzimidazoles.

Tuncbilek M., Göker A. H., Ertan R., Eryigit R., Kendi E., Altanlar N.

Archiv der Pharmazie, vol.330, no.12, pp.372-6, 1997 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 330 Issue: 12
  • Publication Date: 1997
  • Doi Number: 10.1002/ardp.19973301203
  • Journal Name: Archiv der Pharmazie
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.372-6
  • Keywords: antifungal and antimicrobial activity, anilino benzimidazoles, X-ray structure analysis
  • Ankara University Affiliated: Yes

Abstract

A series of 2-(anilino or 2,6-dichloroanilino)-1,5(6)-disubstituted-1H-benzimidazoles (1-13) were prepared by reaction of several 2-chloro-or 2-chloromethyl-1H-benzimidazoles with aniline derivatives. The prepared compounds were screened for their in vitro antibacterial and antifungal activities. Compounds 2, 8, and 9 exhibited the best activity.