Study on electrooxidation of cefadroxil monohydrate and its determination by differential pulse voltammetry

Ozkan S. A., Erk N., Uslu B., Yilmaz N., Biryol I.

Journal of Pharmaceutical and Biomedical Analysis, vol.23, no.2-3, pp.263-273, 2000 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 2-3
  • Publication Date: 2000
  • Doi Number: 10.1016/s0731-7085(00)00294-6
  • Journal Name: Journal of Pharmaceutical and Biomedical Analysis
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.263-273
  • Keywords: cefadroxil monohydrate, electrooxidation, differential pulse voltammetry (DPV), UV spectraphotometry, determination, CEFTRIAXONE
  • Ankara University Affiliated: Yes

Abstract

In this work electrooxidation of cefadroxil monohydrate was investigated using a glassy carbon electrode depending on pH and supporting electrolyte. It was shown that the direct determination of the substance from capsules and in oral suspension could be made by differential pulse voltammetry (DPV). UV and first derivative UV spectrophotometric methods are also proposed as comparative methods. Copyright (C) 2000 Elsevier Science B.V.