The Role of <sup>18</sup>F-FLT PET/CT in Assessing Early Response to Transarterial Radioembolization and Chemoembolization in Patients with Primary and Metastatic Liver Tumors

NAK D., KÜÇÜK N. Ö., ÇELEBİOĞLU E. C., BİLGİÇ M. S., HAYME S., KIR K. M.

Molecular Imaging and Radionuclide Therapy, vol.31, pp.207-215, 2022 (ESCI) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31
  • Publication Date: 2022
  • Doi Number: 10.4274/mirt.galenos.2022.85579
  • Journal Name: Molecular Imaging and Radionuclide Therapy
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.207-215
  • Keywords: F-18-FLT PET/CT, early response, primary, metastatic, chemoembolization, liver tumors, radioembolization, TACE, TARE, HEPATOCELLULAR-CARCINOMA, Y-90 RADIOEMBOLIZATION, CELLULAR PROLIFERATION, CANCER, MANAGEMENT, WORLDWIDE, CT
  • Ankara University Affiliated: Yes

Abstract

Objectives: Metastases and primary malignancies are common in the liver. Local ablative applications such as transarterial chemoembolization (TACE), and transarterial radioembolization (TARE) provide minimally invasive and safe treatment in unresectable liver tumors. Early detection of response to treatment prevents unnecessary toxicity and cost in non-responder patients and provides an earlier use of other options that may be effective. This study aimed to identify the role of F-18-fluorothymidine (FLT) positron emission tomography/computed tomography (PET/CT) in the assessment of early response to TACE and TARE treatments in patients with unresectable primary and metastatic liver tumors.