9-Deaza-5′-noraristeromycin

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Tuncbilek M., Schneller S. W.

Bioorganic and Medicinal Chemistry, vol.11, no.15, pp.3331-3334, 2003 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 11 Issue: 15
• Publication Date: 2003
• Doi Number: 10.1016/s0968-0896(03)00268-2
• Journal Name: Bioorganic and Medicinal Chemistry
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.3331-3334
• Ankara University Affiliated: Yes

Abstract

9-Deaza-5′-noraristeromycin (2) has been prepared in 10 steps from the readily available (+)-(1R,4S)-4-t-butyldimethylsilyloxycyclopent-2-en-1-yl acetate. Compound 2 was evaluated against a large number of viruses. No activity was found nor did 2 display cyctotoxicity towards the viral host cells. © 2003 Elsevier Science Ltd. All rights reserved.