Development of Hodgkin's Lymphoma Under Bexarotene Treatment for Sezary Syndrome and Review of the Literature

Sanli H., AKAY B. N., ÖZCAN M.

JOURNAL OF DRUGS IN DERMATOLOGY, vol.9, no.8, pp.1014-1016, 2010 (SCI-Expanded) identifier

  • Publication Type: Article / Review
  • Volume: 9 Issue: 8
  • Publication Date: 2010
  • Journal Name: JOURNAL OF DRUGS IN DERMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1014-1016
  • Ankara University Affiliated: Yes

Abstract

There are several reports of patients who developed extracutaneous lymphoma after they started bexarotene treatment. The authors report a case in which the initiation of bexarotene therapy for Sezary syndrome was temporally associated with the development of Hodgkin's lymphoma despite improvement in cutaneous signs and symptoms. It is possible that bexarotene may contribute to the development of extracutaneous lymphoma. Although bexarotene therapy may relieve symptoms and signs of cutaneous T-cell lymphoma, careful examination of the lymph nodes during treatment is recommended.