SYNTHESIS AND ANTIMICROBIAL EVALUATION OF SOME NOVEL SULFONYLAMIDO-BENZOXAZOLES

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ARPACI Ö., Doganc F., Sac D., Sari E., KAYNAK ONURDAĞ F., ÖKTEN S.

ACTA BIOLOGICA HUNGARICA, vol.67, no.1, pp.75-84, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 67 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.1556/018.67.2016.1.6
  • Journal Name: ACTA BIOLOGICA HUNGARICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.75-84
  • Keywords: Benzoxazole, sulfonylamides, antibacterial activity, antifungal activity, synthesis, ANALOGS
  • Ankara University Affiliated: Yes

Abstract

A series of 2-(p-substituted phenyl)-5-[(4-substituted phenyl) sulfonylamido]-benzoxazoles were synthesized and tested for their antimicrobial activities. The structures of the new derivatives were elucidated by spectral techniques. The minimum inhibitory concentrations (MIC) of the new benzoxazoles were determined against standard bacterial and fungal strains and drug-resistant isolates and compared to those of several reference drugs.