Does dipyrone have any effect on respiratory function in COPD patients?

Creative Commons License

Gulmez S., Tulunay F., Beder S., KAYACAN O., Karnak D.

RESPIRATORY MEDICINE, vol.100, no.5, pp.828-834, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 100 Issue: 5
  • Publication Date: 2006
  • Doi Number: 10.1016/j.rmed.2005.09.002
  • Journal Name: RESPIRATORY MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.828-834
  • Keywords: dipyrone (metamizole), chronic obstructive pulmonary disease (COPD), bronchodilation, spirometry
  • Ankara University Affiliated: Yes

Abstract

Objective: Dipyrone (Novalgin((R))) is an effective analgesic, antipyretic agent also with spasmolytic effects on various types of smooth muscles. It has recently been reported that dipyrone relaxes tracheal smooth muscle of guinea pig. In this present study, we aimed to investigate whether this and previously reported in vitro results have any consequences on the respiratory function of normal healthy volunteers and chronic obstructive pulmonary disease (COPD) patients.