Relapsing hepatitis A: Three case reports Uzamiş hepati̇t A: Üç olgu raporu

Yeşikaya A., Demir G., MEMİKOĞLU K. O., YÖRÜK F., Sözen T. H.

Mikrobiyoloji Bulteni, vol.37, no.4, pp.301-307, 2003 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 4
  • Publication Date: 2003
  • Journal Name: Mikrobiyoloji Bulteni
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.301-307
  • Keywords: Prolonged hepatitis A, Relapsing hepatitis A
  • Ankara University Affiliated: Yes


In this report, three patients, admitted to Ankara University Faculty of Medicine, Ibni Sina Hospital, Clinical Bacteriology and Infectious Diseases Department, with the diagnosis of acute viral hepatitis A have been discussed because of their clinical and/or biochemical relapses. Following conservative treatment and bedrest, the liver transaminases decreased to nearly normal levels but a second peak was observed later in three of the cases. Other viral, metabolic and autoimmune factors which could lead to the increase of liver transaminases were ruled out. Anti-HAV IgM antibodies became negative in 2 to 4 months later, and liver enzymes returned to normal in 4 to 5 months after onset of their illnesses. As a result, it was concluded that conservative follow-up and therapy would be sufficient since the prognosis of A hepatitis is usually benign even if it relapsed.