The coexistence of thymic carcinoma and multiple granulomas in a Turkish child.

Tacyildiz N., Ugur H., Yavuz G., Unal E., Comba A., Okten I., ...More

Pediatric hematology and oncology, vol.24, no.4, pp.301-7, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 4
  • Publication Date: 2007
  • Doi Number: 10.1080/08880010701440882
  • Journal Name: Pediatric hematology and oncology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.301-7
  • Keywords: childhood, thymic carcinoma, thymic granulomas, EPITHELIAL NEOPLASMS, TUBERCULOSIS, EXPERIENCE, GIRL
  • Ankara University Affiliated: Yes

Abstract

□ Thymic carcinoma, which is a thymic epithelial neoplasm with obvious cytologic atypia, is a rare neoplasm. The authors report on a 10-year-old boy who presented with respiratory distress due to bulky anterior mediastinal mass. Histological and immunohistochemical studies confirmed a lymphoepithelioma-like pattern thymic carcinoma. In addition, evaluation of the specimen showed foci of caseation and multiple granulomas with extensive central necrosis within the thymic tissue. The child received chemotherapy, followed by surgery and radiotherapy. To rule out difficulties of tuberculosis he also received antituberculosis therapy. Two years after cessation of treatment, he is still in remission for thymic carcinoma. Copyright © Informa Healthcare.