Evaluation of the level of dynamic thiol/disulphide homeostasis in adolescent patients with newly diagnosed primary hypertension

Cakici E. K., Eroglu F. K., Yazilitas F., Bulbul M., Gur G., AYDOĞ Ö., ...More

PEDIATRIC NEPHROLOGY, vol.33, no.5, pp.847-853, 2018 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 5
  • Publication Date: 2018
  • Doi Number: 10.1007/s00467-017-3865-3
  • Journal Name: PEDIATRIC NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.847-853
  • Keywords: Oxidative stress, Dynamic thiol/disulphide, Oxidized thiol, Blood pressure, Adolescents, BLOOD-PRESSURE, OXIDATIVE STRESS, PLASMA, SUPPLEMENTATION, PATHOGENESIS, CHILDREN
  • Ankara University Affiliated: Yes

Abstract

Background Thiol/disulphide homeostasis plays a critical role in numerous intracellular enzymatic pathways including antioxidant defense and detoxification. This study was designed to investigate the impact of thiol/disulfide homeostasis in adolescent patients with recently diagnosed primary hypertension (HT) using a novel and automated method.