Effects of levetiracetam and valproic acid treatment on liver function tests, plasma free carnitine and lipid peroxidation in childhood epilepsies

Haznedar P., DOĞAN Ö., Albayrak P., Tuncer G. O., TEBER S., Deda G., ...More

EPILEPSY RESEARCH, vol.153, pp.7-13, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 153
  • Publication Date: 2019
  • Doi Number: 10.1016/j.eplepsyres.2019.03.009
  • Journal Name: EPILEPSY RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.7-13
  • Keywords: Carnitine, Epilepsy, Levetiracetam, Oxidative stress, Valproic acid, 8-OHdG, INCREASED OXIDATIVE STRESS, ANTIEPILEPTIC DRUGS, POSTSTROKE SEIZURES, DNA-DAMAGE, CHILDREN, MONOTHERAPY, CARBAMAZEPINE, MANAGEMENT, LEVEL
  • Ankara University Affiliated: Yes

Abstract

Background and aims: The relationship between anti-epileptic usage and oxidative damage has not yet been clearly understood. In our study, we investigated oxidative stress parameters, carnitine levels, liver function tests (LFT) and their relationship in epileptic children treated with valproic acid or levetiracetam.