Colonic melanoma, primary or regressed primary

Poggi S. H., Madison McNiff J. F., Hwu W. P., Bayar S., Salem R. R.

Journal of Clinical Gastroenterology, cilt.30, sa.4, ss.441-444, 2000 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 4
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1097/00004836-200006000-00019
  • Dergi Adı: Journal of Clinical Gastroenterology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.441-444
  • Anahtar Kelimeler: Gastrintestinal tumors, Mucosal melanoma, Pathologic features, Primary colonic melanoma
  • Ankara Üniversitesi Adresli: Hayır

Özet

Primary melanoma originating in the gastrointestinal tract is very rare and the majority of these tumors arise in the mucosa of the anus or rectum. A case of solitary colonic melanoma in a 79-year-old man is described with a review of pertinent literature. The surgically excised neoplasm was evaluated by routine histology and immunohistochemistry stains. Pathologic examination of the excised cecal mass revealed an 8 x 5-cm tan-pink mass with a central green-black necrotic area. Histologically, there were solid sheets of S100- and HMB-45-positive pigmented cells extending from the mucosal ulcerated surface through the bowel wall. The patient had no evidence of cutaneous or ocular primary melanoma. He remained free of recurrent disease 5 years after surgical resection of the colonic melanoma. The unique pathologic features and clinical outcome support the diagnosis of primary colonic melanoma in this patient.