Akademik Veri Yönetim Sistemi
Tezin Türü: Yüksek Lisans
Tezin Yürütüldüğü Kurum: Ankara Üniversitesi, Nükleer Bilimler Enstitüsü, Medikal Fizik Bölümü, Türkiye
Tezin Onay Tarihi: 2024
Tezin Dili: Türkçe
Öğrenci: CENNET İLTEMİŞ
Danışman: Haluk Yücel
Özet:
This thesis aims to achieve more
precise and accurate dose evaluations in the treatment and diagnosis of head
and neck cancers. Ionizing radiation, particularly photon radiation, is
frequently used in medical diagnostics. In this study, a head and neck phantom
was created for an adult male, and the therapeutic doses delivered to the C2
vertebra corpus in radiotherapy were analyzed. This phantom is critically
important for verifying radiotherapy plans and ensuring quality assurance in
the treatment of head and neck cancers. The phantom, representing the
anatomical structures of the head and neck region, was produced using two
different tissue-equivalent materials and was fabricated via 3D printing
technologies (FDM and SLA) alongside molding techniques. Additionally, dose
measurements were performed in a LINAC system using a 6 MV photon energy beam,
following various treatment planning protocols. These measurements were
evaluated using an ion chamber, a small field radiation dosimeter compatible
with Exradin W1 detector plastic scintillator dosimetry, and EBT3 radiochromic
film to assess the absorbed doses in target and at-risk organs. When a dose of
24 Gy was given to target PTV volume at
6 MV photon beam quality, 22.54 Gy is measured at C2 Vertabra Corpus, 1.76
Gy at Oral Cavity, 7.04 Gy at Right Parotid Gland and 11.74 Gy at Left Parotid
Gland by using PSD ExradinW1. Although the measured doses differed by 3-32%
compared with those calculated ones with TPS, their amounts were found to be non-negligible. In the
thesis, the doses measured in target risk at organs(OARs) at risk with EBT3
film and ion chamber are also given in detail.